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Thermo Scientific™ GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 Cells

GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 6 (P2RY6) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.

Brand:  Thermo Scientific™ K1717

Product Code. 10043873

  • 144600.00 SEK / Each
Estimated Shipment: 14-01-2025
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For Research Use Only. All usage must comply with product instructions.

This item is not returnable. View return policy

Description

Description

GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 6 (P2RY6) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of UDP. In addition, GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

P2RY6 has been found in a variety of rat tissue such as; placenta, spleen, thymus, lung, stomach, intestine, mesentery, heart, and aorta. P2RY6 is activated by UDP, which functions as a full agonist. P2RY6 is activated either weakly or not at all by additional extracellular nucleotides such as UTP, ATP, and ADP. P2RY6 has been implicated to be involved in ion transport, vasodilatation, and contraction of smooth muscle.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_004154.3
Dividing Cells
Fluorescence
P2RY6
Single Cell Clone Origin
2 x 106 Cells
P2RY6
CHO-K1
GPCR
Cell-based beta lactamase reporter gene
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol/

Includes:
• GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells
• GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
FRET
P2RY6-NFAT-bla CHO-K1 cells, P2RY6-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis
GeneBLAzer™
BLA (Beta-Lactamase)
Dividing Cells
GeneBLAzer™
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For Research Use Only. Not for use in diagnostic procedures.