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Tocris Bioscience™ GLPG 0974
Potent FFA2 antagonist
Brand: Tocris Bioscience™ 5621/10
This item is not returnable.
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Description
GLPG 0974 is a potent FFA2 antagonist (IC50 = 9 nM). Exhibits selectivity for FFA2 over FFA3. Inhibits acetate-induced human neutrophil migration in plasma or buffer. Also inhibits FFA2-induced expression of CD11b activation-specific epitope (AE) in human whole blood. Orally bioavailable.Specifications
| 4-[[[(2R)-1-(Benzo[b]thien-3-ylcarbonyl)-2-methyl-2-azetidinyl]carbonyl][(3-chlorophenyl)methyl]amino]butanoic acid | |
| 1391076-61-1 | |
| 10 mg |