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Glucagon Receptor Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA533594
This item is not returnable.
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Description
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Horse, Opossum (94%).
Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.
Specifications
| Glucagon Receptor | |
| Polyclonal | |
| Unconjugated | |
| GCGR | |
| GCGR; GGR; GL-R; Glucagon receptor; glucagon receptor perhaps same as Niddm3; GR | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2642 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| PBS with 0.1% sodium azide | |
| P47871 | |
| GCGR | |
| Synthetic 18 amino acid peptide from N-terminal extracellular domain of human Glucagon Receptor. | |
| 50 μg | |
| Primary | |
| Human, Non-human Primate | |
| Antibody | |
| IgG |