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  7. Histamine, Thermo Scientific Chemicals

Histamine, Thermo Scientific Chemicals

Product Code. 15434269
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Quantity:
1 g
5 g

Description

Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Solubility
Soluble in water, alcohol, and hot chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Hygroscopic. Handle and store under inert gas. Air sensitive.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 51-45-6
Molecular Formula C5H9N3
Molecular Weight (g/mol) 111.15
MDL Number MFCD00005210,MFCD00128939
InChI Key NTYJJOPFIAHURM-UHFFFAOYSA-N
Synonym histamine, 1h-imidazole-4-ethanamine, 2-4-imidazolyl ethylamine, ergotidine, 2-1h-imidazol-5-yl ethanamine, ergamine, eramin, 5-imidazoleethylamine, theramine, free histamine
PubChem CID 774
ChEBI CHEBI:18295
SMILES NCCC1=CN=CN1

Specifications

Color White
Quantity 1 g
UN Number UN2811
Beilstein 2012
Merck Index 14,4719
Solubility Information Soluble in water,alcohol,and hot chloroform.
IUPAC Name 2-(1H-imidazol-5-yl)ethanamine
Formula Weight 111.15
Physical Form Powder
Chemical Name or Material Histamine

Safety and Handling

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Product Identifier
  • Histamine
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
  • Serious eye damage/eye irritation Category 1
  • Respiratory sensitiser Category 1
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H301-Toxic if swallowed.
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H318-Causes serious eye damage.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P270-Do not eat, drink or smoke when using this product.
  • P272-Contaminated work clothing should not be allowed out of the workplace.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contains : 1H-Imidazole-4-ethanamine

RUO – Research Use Only

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