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Gibco™ Human FGF-19 Recombinant Protein, PeproTech®
E. coli Recombinant Protein
814.00 SEK - 30600.00 SEK
Specifications
Accession Number | O95750 |
---|---|
For Use With (Application) | Functional Assay |
Formulation | protein with no preservative |
Gene ID (Entrez) | 9965 |
Molecular Weight (g/mol) | 21.8 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17860673
|
Gibco™
100-32-100UG |
100 μg |
6120.00 SEK
100µg |
In Stock Log in to see stock. |
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17831773
|
Gibco™
100-32-1MG |
2 x 500 μg |
30600.00 SEK
1mg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
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17861483
|
Gibco™
100-32-250UG |
250 μg |
10720.00 SEK
250µg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
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17871753
|
Gibco™
100-32-25UG |
25 μg |
2005.00 SEK
25µg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
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17840883
|
Gibco™
100-32-500UG |
500 μg |
18340.00 SEK
500µg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
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17890383
|
Gibco™
100-32-50UG |
50 μg |
3685.00 SEK
50µg |
In Stock Log in to see stock. |
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17850703
|
Gibco™
100-32-5UG |
5 μg |
814.00 SEK
5µg |
Estimated Shipment: 16-09-2024 Log in to see stock. |
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Description
FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity. The orthologous protein in mouse is FGF15, which shares about 50% amino acid identity and has similar functions. Together they are often referred to as FGF15/19.Specifications
O95750 | |
protein with no preservative | |
21.8 | |
E. coli | |
RUO | |
FGF; Fgf15; FGF19; FGF-19; Fibroblast growth factor; fibroblast growth factor 15; fibroblast growth factor 19; UNQ334/PRO533 | |
Human | |
Recombinant | |
Lyophilized |
Functional Assay | |
9965 | |
Human FGF-19 | |
-20°C | |
<1 EU/μg | |
FGF19 | |
Unconjugated | |
MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK | |
≥ 95% by SDS-PAGE gel and HPLC analyses. |