missing translation for 'onlineSavingsMsg'
Learn More

Proteintech HumanKine™ recombinant human IGF-I protein

HumanKine™ recombinant protein

Brand:  Proteintech HZ-1322-100UG

 View more versions of this product

Product Code. 17690087

  • 674.52 SEK / 100µg

Please to purchase this item. Need a web account? Register with us today!

Explore more special offers
This item is not returnable. View return policy

Description

Description

The Insulin like growth factor-1, also known as Somatomedin-C is a growth factor which is structurally related to insulin and is an important regulator of growth and differentiation in various tissues and cell systems. Human IGF-1 is synthesized as two precursor isoforms with N- and alternate C-terminal propeptide. The two precursor isoforms are differentially expressed by various tissues. The proteolytic cleavage of the N- and C-terminal regions results in the mature IGF-1 protein which is identical between isoforms. IGF-1 binds to IGF-1 receptor and induces receptor autophosphorylation. This further phosphorylates Insulin receptor substrate -1 (IRS-1) and activates various downstream signaling pathways including the PI3-AKT, MAPK etc. (PMID: 17354613, 17113337, 29535161)
Specifications

Specifications

P05019
3479
100 μg
Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
Human
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Lyophilized
1 x PBS pH 7.4
10 kDa
HEK293
<1 EU/μg
Recombinant
2-14 ng/mL EC50
>95%
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.