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ICA 069673
KV7.2/KV7.3 channel opener
1520.00 SEK - 5085.00 SEK
Specifications
Chemical Name or Material | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide |
---|---|
CAS | 582323-16-8 |
Assay Percent Range | >99% |
Molecular Formula | C11H6ClF2N3O |
Formula Weight | Observed MW: 269.63 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18717046
|
Tocris Bioscience
4305/25 |
25 mg |
5085.00 SEK
25mg |
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18795356
|
Tocris Bioscience
4305/5 |
5 mg |
1520.00 SEK
5mg |
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Description
Selective KV7.2/KV7.3 (KCNQ2/3) channel opener (EC50 = 0.69 μM). Exhibits 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5, with no measurable activity over a panel of cardiac ion channels. Hyperpolarizes resting membrane potential and inhibits spontaneous action potentials in guinea pig detrusor muscle (DSM) isolated cells. Orally active in animal models of epilepsy.Specifications
N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide | |
>99% | |
Observed MW: 269.63 |
582323-16-8 | |
C11H6ClF2N3O |
Safety and Handling
Recommended Storage : Store at Room Temperature
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Product Title
ICA 069673