missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ Imipramine hydrochloride
Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment
Brand: Tocris Bioscience™ 7841/50
This item is not returnable.
View return policy
Description
Imipramine hydrochloride is a potent tricyclic antidepressant; inhibits 5-HT and noradrenalin transporters (Ki values = 1.3-20 nM and 20-142 nM respectively). Increases autophagy, both alone and in combination with VEGF inhibitors or Temozolomide (Cat. No. 2706), to reduce the progression of glioma and slow the proliferation of other tumors. Reprograms tumor-associated macrophages from immunosuppressive to immunostimulatory via histamine receptor inhibition.Specifications
| 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride | |
| 50 mg | |
| C19H24N2.HCl |
| 113-52-0 | |
| Autophagy-related Compounds |