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Tocris Bioscience™ INDY

DYRK1A/B inhibitor

Brand: Tocris Bioscience™ 4997/10

Product Code. 18717557

2505.00 SEK / 10mg

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Description

INDY is a DYRK1A/B inhibitor (IC50 values are 0.23 and 0.24 μM, for DYRK1B and DYRKA respectively). Binds at the ATP-binding cleft of the enzyme. Reverses aberrant tau-phosphorylation and rescues repressed calcineurin/NFAT signaling. Impairs the self-renewal capacity of subventricular zone neural stem cells. Also available as a prodrug, proINDY (Cat. No. 4998).

Specifications

Purity	>98%
Product Type	INDY
Inhibitors	INDY

Quantity	10 mg
Molecular Weight (g/mol)	235.3

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Tocris Bioscience™ INDY

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