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Thermo Scientific™ iPrPAC dG Phosphoramidite
iPrPAC dG is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Isopropylphenoxyacetyl (iPrPAC) base protection, for use in oligonucleotide synthesis.
Brand: Thermo Scientific™ 27-1726-06
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Description
- iPrPAC-dG CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Isopropylphenoxyacetyl (iPrPAC) base protection, for use in oligonucleotide synthesis.
- The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions.
- Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05 M potassium carbonate in methanol.
- The 'Standard Grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements.
- Features:
- Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isopropylphenoxyacetyl-2'-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- Molecular formula: C51H60N7O9P
- Base: dG
- Base Protection: iPrPAC
- Formula weight: 946.05 g/mol
- CAS number: 150065-82-0
- HPLC Purity: ≥98.0%
- 31P NMR Purity: ≥98.0%
Specifications
| 5′-O-(4,4′-Dimethoxytrityl)-N2-isopropylphenoxyacetyl-2′-deoxyguanosine-3′-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | |
| 946.05 g/mol | |
| ≥98.0% | |
| 10 g |