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Tocris Bioscience™ JQ1-FITC

Fluorescent BET bromodomain probe; suitable for use in TR-FRET

Brand: Tocris Bioscience™ 7722/2

Product Code. 18075662

3453.91 SEK / 2mg

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Description

JQ1-FITC is a fluorescent BET bromodomain probe. It binds with high affinity to BRD4(BD1) and BRD4(BD2) (KD,app values are 6.5 nM and 5.8 nM, respectively, using GST-tagged BRD4 proteins measured by CoraFluor™ TR-FRET assay; 58.7 nM for BRD4(BD1) in a fluorescence anisotropy assay). Excitation and emission maxima (λ) are 495 nm and 525 nm.

Specifications

Chemical Name or Material	(S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate
Target	Fluorescent Probes
Purity	95%

Quantity	2 mg
Molecular Formula	C₅₀H₅₀ClN₇O₉S₂.CF₃CO₂H

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