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Tocris Bioscience™ KYL

EphA4 kinase inhibitor; neuroprotective

Brand: Tocris Bioscience™ 5290/1

Product Code. 18768088

2265.00 SEK / 1mg

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Description

KYL is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.

Specifications

Description	KYL
Product Type	KYL
Sequence	Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu

Molecular Weight (g/mol)	1465.75
Quantity	1 mg

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Tocris Bioscience™ KYL

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