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Malononitrile, 99%, Thermo Scientific Chemicals
Description
Crosslinking agent for modification of proteins via amidationMalononitrile is used as a precursor in the preparation of anti-cancer drug, triamterene, adenine, methotrexate, thiamine, acrylic fibers and dyes. It is used in Knoevenagel condensation to prepare 2-chlorobenzalmalononitrile by reacting with 2-chlorobenzaldehyde. It acts as a leaching agent for gold. It is used as a raw material for the Gewald reaction of ketone or aldehyde to produce 2-aminothiophene using elemental sulfur and a base. Further, it plays an important role in the preparation of [1,6]-naphthyridines, gamma-ketoamides, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Crosslinking agent for modification of proteins via amidationMalononitrile is used as a precursor in the preparation of anti-cancer drug, triamterene, adenine, methotrexate, thiamine, acrylic fibers and dyes. It is used in Knoevenagel condensation to prepare 2-chlorobenzalmalononitrile by reacting with 2-chlorobenzaldehyde. It acts as a leaching agent for gold. It is used as a raw material for the Gewald reaction of ketone or aldehyde to produce 2-aminothiophene using elemental sulfur and a base. Further, it plays an important role in the preparation of [1,6]-naphthyridines, gamma-ketoamides, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks.
Solubility
Soluble in water, acetone, acetic acid, chloroform, ethanol, ether and benzene.
Notes
Store in a cool place. Incompatible with strong oxidizing agents, strong reducing agents, strong acids and strong bases.
Specifications
Specifications
| Melting Point | 30°C to 34°C |
| Density | 1.049 |
| Boiling Point | 220°C to 222°C |
| Flash Point | 112°C (233°F) |
| Refractive Index | 1.415 |
| Quantity | 100 g |
| UN Number | UN2647 |
| Beilstein | 773697 |
| Merck Index | 14,5711 |
| Solubility Information | Soluble in water,acetone,acetic acid,chloroform,ethanol,ether and benzene. |
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Safety and Handling
- Malononitrile
- Danger
- Acute toxicity Category 3
- LONG-TERM AQUATIC HAZARD Chronic 1
- ACUTE AQUATIC Acute 1
- H301-Toxic if swallowed.
- H311-Toxic in contact with skin.
- H331-Toxic if inhaled.
- H400-Very toxic to aquatic life.
- H410-Very toxic to aquatic life with long lasting effects.
- P273-Avoid release to the environment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- MIXTURE LIST-Contains : Propanedinitrile
RUO – Research Use Only
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