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  6. ML 120B dihydrochloride, Tocris Bioscience™

ML 120B dihydrochloride, Tocris Bioscience™

Product Code. 30002045
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Novel IKK2-selective inhibitor

Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 μM ATP). Exhibits no inhibition at IKK1 (EC50 >100 μM), IKKε (EC50 >100 μM) or a panel of 28 other kinases (EC50 >50 μM). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).

Chemical Identifiers

CAS 783348-36-7
Molecular Formula C19H15ClN4O2
Molecular Weight (g/mol) 366.81
InChI Key ZNOLRTPMNMPLHY-UHFFFAOYSA-N
Synonym mln120b, mln-120b, n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methylnicotinamide, ml 120b dihydrochloride, n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methyl-3-pyridinecarboxamide, d0t8is, mln 120b, znolrtpmnmplhy-uhfffaoysa-n, n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methyl-nicotinamide, n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methylnicotinamide
PubChem CID 9929127

Specifications

Quantity 50 mg
Formula Weight 439.72
Chemical Name or Material ML 120B dihydrochloride
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