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  7. 18736658

Tocris Bioscience™ (±)-ML 209

RORγt inverse agonist; suppresses Th17 cell differentiation

Brand:  Tocris Bioscience™ 5987/50

5958.38 SEK valid until 2024-12-16
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Product Code. 18736658

  • 7530.00 SEK / 50mg

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Description

Description

(±)-ML 209 is a RORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).
Specifications

Specifications

White
1334526-14-5
441.52g/mol
Store at 4°C
50 mg
Inhibitor
C25H31NO6
Soluble to 100mM in DMSO
Agonist against RORγt
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For Laboratory Research Use Only