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ML 323
Potent and selective USP1-UAF1 allosteric inhibitor
788.00 SEK - 2620.00 SEK
Specifications
| CAS | 1572414-83-5 |
|---|---|
| Synonym | 5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine |
| Molecular Formula | C23H24N6 |
| Formula Weight | 384.48 |
| Purity | 98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18781408
|
Tocris Bioscience
6435/5 |
5 mg |
788.00 SEK
5mg |
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|
18701748
|
Tocris Bioscience
6435/25 |
25 mg |
2620.00 SEK
25mg |
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Description
Potent and selective allosteric inhibitor of USP1-UAF1 deubiquitinase complex (IC50 = 76 nM). Exhibits selectivity for USP1-UAF1 over a panel of enzymes, including other deuquitinating enzymes. Inhibits deubiquitination of PCNA and FANCD2 and sensitizes cisplatin-resistant H596 cells to cell death induced by cisplatin (Cat. No. 2251) in vitro.Specifications
| 1572414-83-5 | |
| C23H24N6 | |
| 98% |
| 5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine | |
| 384.48 |
Safety and Handling
Recommended Storage : Store at -20°C