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N-Ras Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA528861
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Description
Recommended positive controls: mouse brain. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (90%), Xenopus laevis (92%), Dog (100%), Pig (100%), Chicken (96%), Bovine (100%), Guinea pig (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.
Specifications
| N-Ras | |
| Polyclonal | |
| Unconjugated | |
| NRAS | |
| ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; Neuroblastoma RAS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; Nras; N-ras; N-ras protein part 4; NRAS1; NS6; RAS; RASN; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18176, 4893 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.41 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7 | |
| P01111, P08556 | |
| NRAS | |
| Full length human N-Ras Recombinant protein. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Product Title
N-Ras Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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