missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Phenylacetamides
  8. 30000926

NCL 00017509, Tocris Bioscience™

Product Code. 30000926
Click to view available options
Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.

Specifications

CAS 1507367-00-1
Molecular Formula C15H12N6O
Linear Formula C15H12N6O
Quantity 1 mg
Synonym 3-6-ethynyl-9h-purin-2-yl amino benzeneacetamide
Solubility Information Soluble to 100mM in DMSO
InChI Key CJQGLUJHMXCLQY-UHFFFAOYSA-N
SMILES C#CC1=C2C(=NC(=N1)NC3=CC=CC(=C3)CC(=O)N)N=CN2
IUPAC Name 2-[3-[(6-ethynyl-7H-purin-2-yl)amino]phenyl]acetamide
Molecular Weight (g/mol) 292.302
PubChem CID 56944360
Formula Weight 292.3
Physical Form Solid
Chemical Name or Material 3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide
Grade >97%
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.