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PANX1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12595-1-AP-150UL
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Description
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.Specifications
PANX1 | |
Polyclonal | |
Unconjugated | |
PANX1 | |
MRS1, pannexin 1, PANX1, PX1, UNQ2529 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
24145 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.14 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q96RD7 | |
PANX1 | |
PANX1 Fusion Protein Ag3174 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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