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PANX1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12595-1-AP-20UL
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Description
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.Specifications
| PANX1 | |
| Polyclonal | |
| Unconjugated | |
| PANX1 | |
| MRS1, pannexin 1, PANX1, PX1, UNQ2529 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 24145 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation | |
| 0.14 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q96RD7 | |
| PANX1 | |
| PANX1 Fusion Protein Ag3174 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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