missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organonitrogen Compounds
  6. N-arylamides
  7. Pyr3, Tocris Bioscience™

Pyr3, Tocris Bioscience™

Product Code. 18043782
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective TRPC3 blocker

Selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). Inhibits TRPC3-mediated Ca2+ influx (IC50 = 0.7 μM) and suppresses activation of nuclear factor of activated T cells (NFAT). Inhibits hypertrophic responses in cardiomyocytes.

Chemical Identifiers

CAS 1160514-60-2
Molecular Formula C16H11Cl3F3N3O3
Molecular Weight (g/mol) 456.627
InChI Key RZHGONNSASQOAY-UHFFFAOYSA-N
Synonym pyr3, d0t7gc, pyr hplc, ethyl 1-4-trichloroprop-2-enamido phenyl-5-trifluoromethyl-1h-pyrazole-4-carboxylate, 1-4-2,3,3-trichloro-1-oxo-2-propen-1-yl amino phenyl-5-trifluoromethyl-1h-pyrazole-4-carboxylic acid, ethyl 1-4-2,3,3-trichloroacryloyl amino phenyl-5-trifluoromethyl-1h-pyrazole-4-carboxylate, ethyl-1-4-2,3,3-trichloroacrylamide phenyl-5-trifluoromethyl-1h-pyrazole-4-carboxylate
PubChem CID 56964346
IUPAC Name ethyl 1-[4-(2,3,3-trichloroprop-2-enoylamino)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate
SMILES CCOC(=O)C1=C(N(N=C1)C2=CC=C(C=C2)NC(=O)C(=C(Cl)Cl)Cl)C(F)(F)F

Specifications

Quantity 50 mg
Formula Weight 456.63
Percent Purity >98%
Chemical Name or Material Pyr3
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.