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Tocris Bioscience™ Deltarasin

High affinity PDEδ-KRAS interaction inhibitor

Brand:  Tocris Bioscience™ 5424/10

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Product Code. 15786816

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Description

Description

Deltarasin is a high affinity PDEδ-KRAS interaction inhibitor (Kd = 41 nM); binds to PDEδ. Reduces proliferation and induces cell death of KRAS-dependent Panc-Tu-1 and Capan-1 pancreatic cancer cells. Attenuates tumor growth of Panc-Tu-1 xenografts in mice.
Specifications

Specifications

Other Ras GTPase Compounds
2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride
Soluble to 100mM in water and to 100mM in DMSO
Bioactive Small Molecule
1440898-82-7
10 mg
Solid
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Research Use Only. Not For Human or Veterinary Use