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R&D Systems™ Pan Caspase Inhibitor Z-VAD-FMK
Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
Brand: R&D Systems™ FMK001
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Description
- Fluoromethyl ketone (FMK)-derivatized peptides are useful tools for studying caspase activity
- Used in tissue cultures to inhibit apoptosis at final working concentrations of 50nM to 100μM
- Regulated by a variety of stimuli, including APAF1, CFLAR/FLIP, NOL3/ARC, IAP, BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin and BIRC7/Livin
Specifications
Store the unopened product at -20 to -70° C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. | |
Pan Caspase | |
Z-VAD-FMK |
1 mg | |
467Da | |
Lyophilized |
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Product Title
For research use only. Not for use in diagnostic procedures
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