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STEMCELL Technologies R848

Immune modulator; Inhibits TLR7 and TLR8

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1583.55 SEK - 5719.95 SEK

Specifications

CAS 144875-48-9
Synonym Resiquimod; S 28463
Molecular Formula C17H22N4O2
Purity ≥98%
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STEMCELL Technologies
73782 		10 mg
1583.55 SEK
10mg
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STEMCELL Technologies
73784 		50 mg
5719.95 SEK
50mg
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Description

Description

  • R848 is an imidazoquinoline and agonist of Toll-like receptors (TLRs) 7 and 8
  • It mimics the pathogen-associated molecular patterns that activate immune cells through TLR7 and TLR8, and thereby acts as an immune-response modifier
  • It demonstrates potent anti-tumor and anti-viral properties (IC50 = 4.2 μM; Seganish et al.) which appear to be mediated predominantly through the induction of cytokines, including interferon (IFN)-α and interleukin (IL)-12 due to stimulation of monocytes, macrophages, and dendritic cells (Bernstein et al.; Hattermann et al.; Nian et al.)
Specifications

Specifications

144875-48-9
Resiquimod; S 28463
C17H22N4O2
≥98%
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