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STEMCELL Technologies R848
Immune modulator; Inhibits TLR7 and TLR8
1529.55 SEK - 5526.90 SEK
Specifications
| CAS | 144875-48-9 |
|---|---|
| Synonym | Resiquimod; S 28463 |
| Molecular Formula | C17H22N4O2 |
| Purity | ≥98% |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17117421
|
STEMCELL Technologies
73782 |
10 mg |
1529.55 SEK
10mg |
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|
17160272
|
STEMCELL Technologies
73784 |
50 mg |
5526.90 SEK
50mg |
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Description
- R848 is an imidazoquinoline and agonist of Toll-like receptors (TLRs) 7 and 8
- It mimics the pathogen-associated molecular patterns that activate immune cells through TLR7 and TLR8, and thereby acts as an immune-response modifier
- It demonstrates potent anti-tumor and anti-viral properties (IC50 = 4.2 μM; Seganish et al.) which appear to be mediated predominantly through the induction of cytokines, including interferon (IFN)-α and interleukin (IL)-12 due to stimulation of monocytes, macrophages, and dendritic cells (Bernstein et al.; Hattermann et al.; Nian et al.)
Specifications
| 144875-48-9 | |
| Resiquimod; S 28463 | |
| C17H22N4O2 | |
| ≥98% |