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Rebastinib, MedChemExpress

MedChemExpress Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1WT and Abl1T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit.

Brand:  Medchem Express HY-13024

Encompass_Preferred

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Product Code. 16405498

  • 2116.25 SEK / 10mg

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Description

Description

Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1WT and Abl1T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit.
Specifications

Specifications

Rebastinib
Off-White
C30H28FN7O3
DCC-2036
CC(C)(C)C1=NN(C(NC(NC2=C(F)C=C(OC3=CC(C(NC)=O)=NC=C3)C=C2)=O)=C1)C4=CC=C5C(C=CC=N5)=C4
553.59
Research
Cancer-Kinase/protease
1020172-07-9
Research
10 mg
DMSO : 50 mg/mL (90.32 mM; ultrasonic and warming and heat to 80°C)
553.59
98.0%
Powder
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Rebastinib, MedChemExpress

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