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  6. Retinoic acid, 97%, Thermo Scientific Chemicals

Retinoic acid, 97%, Thermo Scientific Chemicals

Product Code. 11485290
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Quantity:
0.1 g
0.5 g
2 g

Description

All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells.

Retinoic acid is used in dermatology drugs. It is used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus and lichen psoriasis. It is also employed in promoting the proliferation and differentiation of epithelial cells. In addition to this, it exhibits some preventive effect on skin cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient

• All-trans-retinol is involved in hormonal signaling via the retinoid receptors

• It is an important regulator of cell division and apoptosis

• Deficiency can lead to vision, bone, immune, and skin disorders

Applications

• Suitable for research on cell differentiation, embryonic development, immunology and more

• Laboratory grade quality, for research use only

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 302-79-4
Molecular Formula C20H28O2
Molecular Weight (g/mol) 300.44
MDL Number MFCD00001551
InChI Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
Synonym retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra
PubChem CID 444795
ChEBI CHEBI:15367
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

Specifications

Melting Point 180°C to 182°C
Quantity 0.1 g
Beilstein 2057223
Sensitivity Light sensitive
Merck Index 14,8165
Solubility Information Soluble in ethanol,acetate,dimethyl formamide,dimethyl sulfoxide,chloroform,methanol,acetone and dichloromethane. Insoluble in water and ether.
IUPAC Name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Formula Weight 300.44
Percent Purity 98%
Physical Form Crystalline
Chemical Name or Material Retinoic acid
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Safety and Handling

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Product Identifier
  • Retinoic acid
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Reproductive toxicity Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H312-Harmful in contact with skin.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H361d-Suspected of damaging the unborn child.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
 Supplemental information
  • MIXTURE LIST-Contains : all-trans-Retinoic acid

RUO – Research Use Only

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