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Tocris Bioscience™ Ro 25-6981 maleate

GluN2B-selective NMDA antagonist

Brand: Tocris Bioscience™ 1594/50

7497.00 SEK valid until 2024-12-16
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Product Code. 18003882

9535.00 SEK / 50mg

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Description

Ro 25-6981 maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the GluN2B (formally NR2B) subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations GluN1C/GluN2B and GluN1C/GluN2A respectively. Displays neuroprotectant effects in vivo and in vitro.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Chemical Name or Material	(αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate
Assay Percent Range	>98%
Solubility	Soluble to 100mM in DMSO
Formula Weight	Observed MW: 455.55

CAS	1312991-76-6
Quantity	50 mg
Molecular Formula	C₂₂H₂₉NO₂.C₄H₄O₄

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Tocris Bioscience™ Ro 25-6981 maleate

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