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Tocris Bioscience™ Ro 25-6981 maleate
GluN2B-selective NMDA antagonist
Brand: Tocris Bioscience™ 1594/10
1960.21 SEK valid until 2024-12-16
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Description
Ro 25-6981 maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the GluN2B (formally NR2B) subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations GluN1C/GluN2B and GluN1C/GluN2A respectively. Displays neuroprotectant effects in vivo and in vitro.Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Specifications
| (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate | |
| >98% | |
| Soluble to 100mM in DMSO | |
| Observed MW: 455.55 |
| 1312991-76-6 | |
| 10 mg | |
| C22H29NO2.C4H4O4 |
For Research Use Only