missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Trifluoromethylbenzenes
  8. RS 102895 hydrochloride, Tocris Bioscience™

RS 102895 hydrochloride, Tocris Bioscience™

Product Code. 18054122
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

CCR2b chemokine receptor antagonist

CCR2-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Also inhibits α1A, α1D and 5-HT1A receptors.

Chemical Identifiers

CAS 1173022-16-6
Molecular Formula C21H22ClF3N2O2
Molecular Weight (g/mol) 426.864
InChI Key KRRISOFSWVKYBF-UHFFFAOYSA-N
PubChem CID 16759153
IUPAC Name 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one;hydrochloride
SMILES C1CN(CCC12C3=CC=CC=C3NC(=O)O2)CCC4=CC=C(C=C4)C(F)(F)F.Cl

Specifications

Quantity 10 mg
Synonym rs 102895 hydrochloride, rs102895 hydrochloride, rs-102895 hydrochloride, 1'-4-trifluoromethyl phenethyl spiro benzo d 1,3 oxazine-4,4'-piperidin-2 1h-one hydrochloride, 1'-2-4-trifluoromethyl phenyl ethyl-spiro 4h-3,1-benzoxazine-4,4'-piperidin-2 1h-one hydrochloride, c21h21f3n2o2.clh, rs 102895 hydrochloride hplc , powder, 1 inverted exclamation marka-2-4-trifluoromethyl phenyl ethyl-spiro 4h-3,1-benzoxazine-4,4 inverted exclamation marka-peperidin-2 1h-one, 1'-2-4-trifluoromethyl phenyl ethyl spiro 1h-3,1-benzoxazine-4,4'-piperidine-2-one hydrochloride
Formula Weight 426.86
Percent Purity >99%
Chemical Name or Material RS 102895 hydrochloride
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.