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SKF 83822 hydrobromide, Tocris Bioscience™

Product Code. 18074532
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective D1-like agonist

High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, α1A and α1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys.

Chemical Identifiers

CAS 74115-10-9
Molecular Formula C20H23BrClNO2
Molecular Weight (g/mol) 424.763
InChI Key CFWPKYBBXBANLU-UHFFFAOYSA-N
PubChem CID 12909789
ChEBI CHEBI:64002
IUPAC Name 9-chloro-5-(3-methylphenyl)-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide
SMILES CC1=CC=CC(=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)CC=C.Br

Specifications

Quantity 10 mg
Synonym skf 83822 hydrobromide, skf-83822 hydrobromide, 6-chloro-2,3,4,5-tetrahydro-1-3-methylphenyl-3-2-propenyl-1h-3-benzazepine-7,8-diol hydrobromide, n-allyl-6-chloro-1-3-methylphenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide, 3-allyl-6-chloro-1-3-methylphenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol hydrobromide, 3-allyl-6-chloro-7,8-dihydroxy-1-3-methylphenyl-2,3,4,5-tetrahydro-1h-3-benzazepinium bromide, 6-chloro-1-3-methylphenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol hydrobromide, 6-chloro-7,8-dihydroxy-1-3-methylphenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1h-3-benzazepinium bromide, skf83822 hydrobromide, 1h-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-3-methylphenyl-3-2-propen-1-yl-, hydrobromide 1:1
Formula Weight 424.76
Percent Purity >98%
Chemical Name or Material SKF 83822 hydrobromide
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