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Tocris Bioscience™ Spadin

Potent K2P2.1 (TREK-1) channel blocker

Brand: Tocris Bioscience™ 5594/1

Product Code. 18744858

2445.00 SEK / 1mg

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Description

Spadin is a potent TREK-1 channel blocker (IC50 = 71 nM). Enhances dorsal raphe nucleus 5-HT neurotransmission in mice. Induces hippocampal CREB activation and neurogenesis in adult mice. Exhibits antidepressant effects in mouse models of depression. Brain penetrant.

Specifications

Purity	0.95
Molecular Weight (g/mol)	2012.34
Quantity	1 mg

Description	Spadin
Product Type	Spadin
Sequence	Tyr-Ala-Pro-Leu-Pro-Arg-Trp-Ser-Gly-Pro-Ile-Gly-Val-Ser-Trp-Gly-Leu-Arg

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Tocris Bioscience™ Spadin

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