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Thermo Scientific™ Tango™ CXCR3-bla U2OS Cells
The Tango™ CXCR3-bla U2OS cells contain the human chemokine (C-X-C motif) receptor 3 (CXCR3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Brand: Thermo Scientific™ K1829
Additional Details : Weight : 0.01000kg
Description
This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ CXCR3-bla U2OS cells are functionally validated for Z' and EC50 concentrations of I-TAC (CXCL11). In addition, Tango™ CXCR3-bla U2OS cells have been tested for assay performance under variable conditions. This data are found in the Validation & Assay Performance Summary.
Specifications
NM_001504 | |
Dividing Cells | |
Native Tail | |
FRET | |
G-Protein Coupled Receptor (GPCR) | |
GeneBLAzer™, Tango™ | |
End Point | |
U2OS Cell | |
Tango™ |
Cell-based beta-arrestin recruitment | |
Contents: K1829 Tango™ CXCR3-bla U2OS cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • Tango™ CXCR3-bla U2OS cells • Tango™ CXCR3-bla U2OS Assay Protocol • Certificate of Analysis Storage: The Tango™ CXCR3-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
|
Fluorescence | |
CXCR3 | |
Single Cell Clone Origin | |
8 x 106 Cells | |
CXCR3 | |
U2OS | |
GPCR |
For Research Use Only. Not for use in diagnostic procedures.