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TBX21/T-bet Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13700-1-AP-150UL
This item is not returnable.
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Description
T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal transducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.Specifications
| TBX21/T-bet | |
| Polyclonal | |
| Unconjugated | |
| TBX21 | |
| T bet, T box 21, T box protein 21, T PET, TBET, TBLYM, TBX21, TBX21,T bet, Transcription factor TBLYM | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 30009, 57765 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9JKD8, Q9UL17 | |
| Tbx21 | |
| TBX21,T-bet Fusion Protein Ag4618 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Product Title
TBX21/T-bet Rabbit anti-Human, Mouse, Polyclonal, Proteintech > 150 μL; Unconjugated
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