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TCP-1 theta Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA530403
This item is not returnable.
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Description
Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (97%), Rat (98%), Zebrafish (84%), Xenopus laevis (87%), Chicken (95%), Rhesus Monkey (99%), Chimpanzee (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
TCP-1 theta is theta subunit of the CCT (chaperonin containing TCP1 complex) chaperonin molecule which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of the newly synthesized proteins. Molecular chaperones assist in the protein folding upon ATP hydrolysis and TCP-1 theta may play a role in the assembly of the BBsome, a complex that is involved in ciliogenesis regulating transport vesicles to the cilia. Further, TCP-1 theta is also involved in the folding of actin and tubulin. The intact CCT complex is composed of eight polypeptides in a double ring structure. CCT is important within cells in the folding of the VHL tumor suppressor protein.
Specifications
| TCP-1 theta | |
| Polyclonal | |
| Unconjugated | |
| CCT8 | |
| AI132397; bdav; bette davis; C21orf112; Cct8; Cctq; CCT-theta; Chaperonin containing T-complex polypeptide 1 subunit 8; chaperonin containing TCP1 subunit 8; chaperonin containing TCP1, subunit 8 (theta); chaperonin subunit 8 (theta); D21S246; fa22h09; KIAA0002; PRED71; renal carcinoma antigen NY-REN-15; T-complex protein 1 subunit theta; TCP-1-theta; Tcpq; wu:fa22h09; zgc:56059 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10694 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 0.99 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| P50990 | |
| CCT8 | |
| Recombinant fragment corresponding to a region within amino acids 284 and 527 of Human TCP1 theta | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |