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Tocris Bioscience™ TDI 11861
Soluble adenylyl cyclase inhibitor
Brand: Tocris Bioscience™ 8036/5
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Description
TDI 11861 is a potent and selective soluble adenylyl cyclase (sAC) inhibitor (IC50 values are 3.3 nM and 5.5 nM in biochemical and cellular assays, respectively; Kd = 1.4 nM). Inhibits cellular sAC-specific cAMP accumulation (IC50 = 7 nM) and blocks sperm capacitation in vitro. Cell permeable, not cytotoxic and suitable for both in vivo and in vitro use.
Specifications
(3R)-4-[2-[2-[[3-(2-Amino-6-chloro-4-pyrimidinyl)-1-(difluoromethyl)-1H-pyrazol-4-yl]methyl]phenoxy]ethyl]-3-morpholinemethanol | |
5 mg | |
C22H25ClF2N6O3 |
2857049-72-8 | |
Adenylyl Cyclase Inhibitors | |
98% |
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Product Title
Tocris Bioscience™ TDI 11861 > 5 mg
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