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Tocris Bioscience™ TDZD 8
Selective non-ATP competitive inhibitor of GSK 3β
Brand: Tocris Bioscience™ 6092/10
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Description
TDZD 8 is a selective non-ATP competitive inhibitor of GSK 3β (IC50 = 2 μM); thiadiazolidinone deriviative. Does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. Reduces severity of L-dopa-induced dyskinesia in a Parkinson's disease in vivo model.Specifications
White | |
327036-89-5 | |
222.26g/mol | |
Soluble to 100mM in DMSO, 100mM in ethanol | |
Inhibits GSK 3β |
Inhibitor | |
C10H10N2O2S | |
NP 01139 | |
Store at -20°C | |
10 mg |
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