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TGF alpha Monoclonal Antibody (D20), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA543705
This item is not returnable.
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Description
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Specifications
| TGF alpha | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300 | |
| P01135 | |
| TGFA | |
| Glu24-Ala98 (Accession P01135), with N-terminal His Tag | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b κ |
| Immunohistochemistry (Paraffin), Western Blot | |
| D20 | |
| Unconjugated | |
| TGFA | |
| EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 7039 | |
| -20°C | |
| Liquid |
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