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  8. Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%

Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%

Product Code. 11312727
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Quantity:
1 g
5 g

Description

Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.

Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 298-93-1
Molecular Formula C18H16BrN5S
Molecular Weight (g/mol) 414.33
MDL Number MFCD00011964,MFCD00066662
InChI Key AZKSAVLVSZKNRD-UHFFFAOYSA-M
Synonym thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i
PubChem CID 64965
ChEBI CHEBI:53233
IUPAC Name 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide
SMILES [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1

Specifications

Melting Point ∽195°C (decomposition)
Odor Odorless
Quantity 5 g
Beilstein 3825277
Sensitivity Air, light, and moisture sensitive
Solubility Information Soluble in water,ethanol,2-methoxyethanol and phosphate buffered saline.
Formula Weight 414.33
Percent Purity 98%
Chemical Name or Material Thiazolyl Blue tetrazolium bromide

Safety and Handling

compliance-icons
Product Identifier
  • Thiazolyl Blue tetrazolium bromide
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Specific target organ toxicity Category 3
  • Skin corrosion/irritation Category 2
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P405-Store locked up.
  • P501-Dispose of contents/container to in accordance with local/regional/national/international regulations..

RUO – Research Use Only

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