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TIMP2 Monoclonal Antibody (T2-101), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA513603
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Description
MA5-13603 targets TIMP-2 in Immunoprecipitation and Western blot applications and shows reactivity with Human samples. The MA5-13603 immunogen is native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2.
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Specifications
| TIMP2 | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P16035, P25785 | |
| TIMP2 | |
| Native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2 | |
| 500 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 |
| Immunoprecipitation, Western Blot | |
| T2-101 | |
| Unconjugated | |
| TIMP2 | |
| Collagenase inhibitor; CSC-21K; D11Bwg1104e; DDC8; etID32613.12; fa96h09; Metalloproteinase inhibitor 2; metalloproteinase inhibitor 2a; metalloproteinase inhibitor precursor; metalloproteinase inhibitor TIMP-2; metalloproteinase-2; similar to metalloproteinase inhibitor; testicular secretory protein Li 57; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP metallopeptidase inhibitor 2a; TIMP2; Timp-2; TIMP-2 protein; timp2a; tissue inhibitor of matrix metalloproteinase-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase 2 precursor; tissue inhibitor of metalloproteinase 2a; tissue inhibitor of metalloproteinase-2; tissue inhibitor of metalloproteinase-2 precursor; tissue inhibitor of metalloproteinases 2; tissue inhibitor of mettaloproteinase 2; wu:fa96h09; zgc:136726 | |
| Mouse | |
| Protein G | |
| RUO | |
| 21858, 7077 | |
| 4° C | |
| Liquid |
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