missing translation for 'onlineSavingsMsg'
Learn More
Learn More
GeneBLAzer™ TRα-UAS-bla HEK 293T Assay Kit
GeneBLAzer™ TRα-UAS-bla HEK 293T Assay Kit contains the ligand-binding domain (LBD) of the human Thyroid hormone receptor alpha(TR alpha) fused to the DNA-binding domain of GAL4.
Brand: GeneBLAzer™ K1684
Additional Details : Weight : 0.01000kg
Description
- GeneBLAzer™UAS-bla HEK 293T cells stably express a beta-lactamase reporter gene under the transcriptional control of an upstream activator sequence (UAS).
- When an agonist binds to the LBD of the GAL4 (DBD)-TR alpha (LBD) fusion protein, the protein binds to the UAS, resulting in expression of beta-lactamase.
- TR alpha-UASbla HEK 293T 293 cells are functionally validated for Z' and EC50concentrations of T3 Thryoid hormone.
- In addition, TR alpha-UAS-bla HEK 293T 293 cells have been tested for assay performance under variable conditions, including DMSO concentration, cell number, stimulation time, and substrate loading time (data available upon request).
Specifications
| Dry Ice Storage: -80°C/Liquid Nitrogen | |
| Fluorescent | |
| TR alpha-UAS-bla HEK 293T cells (K1260) | |
| Detection Assay Kit |
| Primary Agonist: All-trans-retinoic Acid; Antagonists: AGN 193109; Reporter: BLA (Beta-Lactamase) | |
| Nuclear Receptors | |
| 1 Plate |