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  6. Thermo Scientific Chemicals Ubiquitin E1 Inhibitor, PYR-41

Thermo Scientific Chemicals Ubiquitin E1 Inhibitor, PYR-41

Product Code. 15406879
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Quantity:
25 mg
100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

PYR 41 is an irreversible and cell-permeable UBE1 inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

  • PYR-41 is a cell permeable inhibitor of Ubiquitin activating enzyme (E1) with little or no activity against E3, E2, or caspase enzymatic activity
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 418805-02-4
Molecular Formula C17H13N3O7·3H2O, C17H13N3O7
Synonym Ubiquitin-Activating Enzyme E1 Inhibitor; PYR-41

Specifications

Quantity 25 mg
Description Dark Purple
Content And Storage -30°C to -10°C
For Use With (Application) PYR-41 is a cell permeable inhibitor of Ubiquitin activating enzyme (E1) with little or no activity against E3, E2, or caspase enzymatic activity.
Formula Weight 425.40g/mol
Sensitivity Light Sensitive
Solubility Soluble in DMSO at 5mg/ml with warming
Product Type Signal Transduction Reagent
Form Solid
InChI Key ARGIPZKQJGFSGQ-UHFFFAOYSA-N
SMILES CCOC(=O)C1=CC=C(C=C1)N1NC(=O)C(=CC2=CC=C(O2)[N+]([O-])=O)C1=O
IUPAC Name ethyl 4-{4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate
Molecular Weight (g/mol) 371.31
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Safety and Handling

compliance-icons
Product Identifier
  • Ubiquitin E1 Inhibitor, PYR-41
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Skin sensitiser Category 1
 Hazard Statement
  • H302-Harmful if swallowed.
  • H317-May cause an allergic skin reaction.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : Ubiquitin E1 Inhibitor, PYR-41

RUO – Research Use Only

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