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Tocris Bioscience™ VU 0546110
Selective SLO3 potassium channel inhibitor
Brand: Tocris Bioscience™ 7956/10
1269.57 SEK valid until 2024-12-16
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Description
VU 0546110 is a selective inhibitor of the sperm-specific potassium channel SLO3 (IC50 = 64 μM). It shows 40-fold selectivity over SLO1. It completely blocks heterologous SLO3 currents and endogenous K+ currents. VU 0546110 inhibits sperm hyperpolarisation and prevents its hyperactivated mobility.Specifications
| 1-[4-[[(4-Methoxyphenyl)thio]methyl]-1-piperidinyl]-2-[4-[(1-methylethyl)sulfonyl]phenyl]ethanone | |
| 10 mg | |
| C24H31NO4S2 |
| 1421523-00-3 | |
| Non-selective/Other Potassium Channel Blockers | |
| 0.98 |