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XRCC1 Monoclonal Antibody (144), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA512071
This item is not returnable.
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Description
A suggested positive control for this product is HT29, LS174T, HeLa cells or normal testis.
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
Specifications
| XRCC1 | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P18887 | |
| XRCC1 | |
| Recombinant human XRCC1 protein | |
| 500 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 144 | |
| Unconjugated | |
| XRCC1 | |
| DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1 | |
| Mouse | |
| Protein A | |
| RUO | |
| 7515 | |
| 4° C | |
| Liquid |