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XRCC1 Monoclonal Antibody (144), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA512071

Product Code. 11304573

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Description

Description

A suggested positive control for this product is HT29, LS174T, HeLa cells or normal testis.

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
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XRCC1 Monoclonal Antibody (144), Invitrogen™ > 500 μL; Unconjugated

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