missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organic acids and derivatives
  6. Carboxylic acids and derivatives
  7. Carboxylic acid amides
  8. Y-26763, Tocris Bioscience™
  • missing translation for 'structureSearchLink'
  • Print

Y-26763, Tocris Bioscience™

Product Code. 18054532
missing translation for 'orderingAttributeHoverText'
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Kir6 (KATP) channel opener

Y-26763 is a Kir6 (KATP) channel opener and active metabolite of Y-27152. Relaxes contracted rat aortic rings (IC50 = 0.027 mM) and inhibits glucose-induced insulin secretion in isolated human pancreatic β-cells in vitro. Produces hypotension in spontaneously hypertensive rats and displays cardioprotective properties in dogs following systemic administration in vivo.

Chemical Identifiers

CAS 127408-31-5
Molecular Formula C14H16N2O4
Molecular Weight (g/mol) 276.292
InChI Key IWTCFIIOUXJOOV-OLZOCXBDSA-N
Synonym unii-q9f3xv8a6x, q9f3xv8a6x, +-3s,4r-n-acetyl-n-hydroxy amino-6-cyano-3,4-dihydro-2,2-dimethyl-2h-1-benzopyran-3-ol, n-3s,4r-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl-n-hydroxyacetamide, acetamide, n-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl-n-hydroxy-, 3s-trans, n-3s,4r-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl-n-hydroxyacetamide, acetamide,n-3s,4r-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl-n-hydroxy, n-3s,4r-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-1-benzopyran-4-yl-n-hydroxyacetamide, d05gpx, n-3s,4r-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl-n-hydroxyacetamide
PubChem CID 121878
IUPAC Name N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-hydroxyacetamide
SMILES CC(=O)N(C1C(C(OC2=C1C=C(C=C2)C#N)(C)C)O)O

Specifications

Quantity 10 mg
Formula Weight 276.29
Percent Purity >98%
Chemical Name or Material Y-26763
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.