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Paxillin Mouse, Unlabeled, Clone: 349, BD
Mouse Monoclonal Antibody
2600.00 SEK - 3985.00 SEK
Specifications
Antigen | Paxillin |
---|---|
Clone | 349 |
Concentration | 1.0mg/mL |
Applications | Western Blot |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15845229
|
BD Biosciences
610051 |
50 μg |
2600.00 SEK
1 set |
Estimated Shipment: 19-09-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
15855229
|
BD Biosciences
610052 |
150 μg |
3985.00 SEK
1 set |
Estimated Shipment: 09-09-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
A number of cytoskeletal proteins are tyrosine phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts. One of these is the 68 kDa paxillin protein. Paxillin is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers. It is also present in the focal adhesions of Madin-Darby canine kidney epithelial cells, but is absent from the cell adherens junctions of these cells. Paxillin purified from chicken gizzard migrates as a diffuse band on SDS-PAGE with molecular weight of 65-70 kDa. It binds to the rod domain of vinculin, another focal adhesion protein. It is thought that phosphorylation of paxillin may have a role in that disassembly of focal adhesions and stress fibers during transformation.Specifications
Paxillin | |
1.0mg/mL | |
Monoclonal | |
Mouse | |
Cell Biology | |
Aqueous buffered solution containing glycerol and ≤0.09% sodium azide. | |
IgG1 | |
Affinity Purified |
349 | |
Western Blot | |
Unconjugated | |
RUO | |
Canine, Chicken, Human, Mouse, Rat | |
Chicken Paxillin aa. 1 to 557 | |
Primary | |
Store undiluted at -20°C. |
For Research Use Only.