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Eurofins DiscoverX CAM KINASE IIA Protein, Active
Active, N-terminal 6His-tagged, recombinant, human CaM kinase IIα full length, expressed by baculovirus in Sf21 insect cells, for use in Kinase Assays.
5796.39 SEK - 44240.30 SEK
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
|---|---|
| Molecular Weight (g/mol) | 55 kDa |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17340864
|
Eurofins DiscoverX
14-962 |
10 μg |
5796.39 SEK
10µg |
Estimated Shipment: 15-08-2024 Log in to see stock. |
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|
17350864
|
Eurofins DiscoverX
14-962M |
250 μg |
44240.30 SEK
250µg |
Estimated Shipment: 15-08-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
CAM KINASE IIA belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
GenBank AF091486.1
Specifications
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| Human | |
| N-terminal 6His | |
| Full-length | |
| CaM Kinase IIα, active |
| 55 kDa | |
| Recombinant | |
| Recombinant enzyme expressed in Sf21 insect cells | |
| ≥77% |