missing translation for 'onlineSavingsMsg'
Learn More

CD33 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1706.43 SEK - 4863.32 SEK

Specifications

Antigen	CD33
Concentration	0.13 mg/mL
Applications	Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
Classification	Polyclonal
Conjugate	Unconjugated

View More Specs

Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
16807324 View Documents missing translation for 'viewProductCertificates'	Proteintech	20 μL	This item is currently unavailable or has been discontinued. View the product page for possible alternatives.		N/A

16897314 View Documents missing translation for 'viewProductCertificates'	Proteintech	150 μL	This item is currently unavailable or has been discontinued. View the product page for possible alternatives.		N/A

Description

CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. CD33 is also expressed on, and is a useful marker for, peripheral monocytes. CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias. Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.

Specifications

Antigen	CD33
Applications	Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
Conjugate	Unconjugated
Host Species	Rabbit
Target Species	Human
Gene Accession No.	P20138
Gene ID (Entrez)	945
Immunogen	CD33 Fusion Protein Ag11490
Primary or Secondary	Primary
Content And Storage	-20°C
Gene	CD33

Concentration	0.13 mg/mL
Classification	Polyclonal
Form	Liquid
Regulatory Status	RUO
Formulation	PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Alias	CD33, CD33 molecule, gp67, p67, SIGLEC 3, SIGLEC3
Gene Symbols	CD33
Isotype	IgG
Purification Method	Antigen Affinity Chromatography
Product Type	Antibody

Spot an opportunity for improvement?Share a Content Correction

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

Your Name

Email Address *

Type of Issue *

Detailed Description of Issue/Request *

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.

CD33 Rabbit anti-Human, Polyclonal, Proteintech

Specifications

Description

Specifications

Documents