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DCP1A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1645.54 SEK - 4652.90 SEK
Specifications
| Antigen | DCP1A |
|---|---|
| Concentration | 0.23 mg/mL |
| Applications | Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16831905
|
Proteintech
22373-1-AP-20UL |
20 μL |
1645.54 SEK
20µL |
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|
16821905
|
Proteintech
22373-1-AP-150UL |
150 μL |
4652.90 SEK
150µL |
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Description
This antibody specifically react with the 70 kDa DCP1A protein.
Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. In particular, Smads influence specific gene transcription by relaying signals from the cell membrane to the nucleus. Smad4 plays an essential role in TGF-beta-induced transcriptional activation wherein phosphorylated receptor-associated Smads associate with Smad4. Furthermore, SMIF (Smad4-intereacting protein) and Smad4 complex with TGF-beta and BMP4. An increase in Smad4 concentration increases the translocation of this complex to the nucleus. SMIF and Smad4 interact directly through a EVH1/WH1 domain on SMIF and a proline-rich activation domain on Smad4. Smad4 is essential to nuclear translocation of SMIF as deletion of the Smad4-interacting domain (located in the N-terminal 100 amino acids) of SMIF eliminates TGF-beta-induced nuclear translocation of SMIF. The human SMIF gene is ubiquitously expressed and encodes a protein with a relative molecular mass of 70 kDa.Specifications
| DCP1A | |
| Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| Unconjugated | |
| Rabbit | |
| Human, Mouse | |
| Q91YD3, Q9NPI6 | |
| 55802, 75901 | |
| DCP1A Fusion Protein Ag18027 | |
| Primary | |
| -20°C | |
| DCP1A |
| 0.23 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| DCP1A, HSA275986, mRNA decapping enzyme 1A, Nbla00360, SMAD4IP1, SMIF, Transcription factor SMIF | |
| DCP1A | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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Product Title
DCP1A Rabbit anti-Human, Mouse, Polyclonal, Proteintech