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  6. Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
  7. 11831255

Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Brand:  Thermo Scientific™ 21658

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Product Code. 11831255

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Description

Description

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

Highlights:

  • Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Crosslink oriented antibodies to Protein A or G agarose
  • Immobilize proteins onto amine-coated surfaces
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-to-Amine
Pierce DSS
Yes
No
11.4Å
Not soluble in water
No
Disuccinimidyl suberate; powder solid
368.34
43mL of typical 1X (1mM) reaction solution (total), or 8 separate uses
8 x 2 mg
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