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Fendiline Hydrochloride
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
Brand: Tocris Bioscience 6407/50
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Description
Fendiline Hydrochloride is a K-Ras inhibitor. Selectively inhibits K-Ras localization to the plasma membrane (IC50 = 9.64 μM). Blocks proliferation of cancer cell lines expressing oncogenic mutant K-Ras. Also inhibits L-type calcium channels (IC50 = 17 μM).Specifications
| Ras GTPase Inhibitors | |
| >98% | |
| C23H25N.HCl |
| 13636-18-5 | |
| 50 mg | |
| Observed MW: 351.91 |